Pharmacoeconomics 2006; 24 (10): 1011-1020

Magnetars as cooling neutron stars with internal heating

We study thermal structure and evolution of magnetars as cooling neutron stars with a phenomenological heat source in a spherical internal layer. We explore the location of this layer as well as the heating rate that could explain high observable thermal luminosities of magnetars and would be consistent with the energy budget of neutron stars. We conclude that the heat source should be located ...

Pharmacoeconomics 2006; 24 (10): 953-954

Pharmacoeconomics 2006; 24 (11): 1043-1053

Pharmacoeconomics 2006; 24 (7): 695-708

Anti-atherogenic effects of the acyl-CoA:cholesterol acyltransferase inhibitor, avasimibe (CI-1011), in cultured primary human macrophages.

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors have been shown to reduce atherosclerotic lesions in animals; however, the mechanism(s) for this effect remains unclear. Therefore, we used cultured primary human monocyte-derived macrophages (HMMs) to examine the effect of the ACAT inhibitor, avasimibe (CI-1011), during foam cell formation and during cholesterol efflux from established foa...